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What painkillers should be taken for late stage liver cancer?

2025-12-17 10:44:53 healthy

What painkillers should be taken for late stage liver cancer?

Patients with advanced liver cancer are often accompanied by severe pain, and rational use of analgesics is an important means to relieve symptoms and improve quality of life. The following is a compilation of hot topics and structured data on analgesics for advanced liver cancer in the past 10 days across the Internet for the reference of patients and their families.

1. Principles of pain management in late stage of liver cancer

What painkillers should be taken for late stage liver cancer?

According to the World Health Organization (WHO) three-step analgesic principle, drugs for late-stage liver cancer pain need to be selected according to the degree:

pain levelRecommended medicineRepresentative medicine
mild painnon-opioid medicationsAcetaminophen, ibuprofen
moderate painWeak opioidscodeine, tramadol
severe painstrong opioidsMorphine, Fentanyl, Oxycodone

2. Comparative analysis of commonly used analgesics

The following are the liver cancer painkillers that have been the most discussed in medical forums in the past 10 days:

Drug nameApplicable stageAdvantagesThings to note
morphine extended release tabletssevere painLong-lasting analgesia (8-12 hours)Be wary of constipation and respiratory depression
Fentanyl transdermal patchsevere pain72 hours sustained releaseAvoid contact with heat sources
Tramadolmoderate painLess addictiveMay cause epileptic seizures

3. Recently popular adjuvant therapies

Search data in the past 10 days show that the following auxiliary treatment methods have seen a significant increase in attention:

therapy typespecific planDiscussion popularity
nerve blockceliac plexus block↑35%
Chinese medicine auxiliaryCorydalis, chelidonine↑28%
psychological interventionmindfulness stress reduction therapy↑42%

4. Medication precautions

1.personalized medicine: The dose needs to be adjusted according to liver function. Patients with Child-Pugh class C should reduce the dose by more than 50%.

2.Prevent side effects: Opioids should be combined with laxatives, and NSAIDs need to monitor renal function

3.Give medication on time: Administration before pain onset is more effective than rescue medication during pain

5. Dietary suggestions for patients

Recent hot topics in nutrition discussions show that the following foods can help alleviate the side effects of drugs:

side effectsRecommended foodMechanism of action
constipationDragon fruit, chia seedsDietary fiber promotes peristalsis
Nausea and vomitingginger, mintInhibits 5-HT3 receptors

6. Latest research trends

1. On August 15, The Lancet published phase II clinical data of the new μ receptor modulator TRV130, which showed that the incidence of nausea was reduced by 40% compared with traditional morphine.

2. The liver-targeted nano-analgesic developed by a domestic team has entered the animal experiment stage and is expected to reduce systemic side effects.

(Note: The specific medication regimen must be strictly followed by the doctor’s instructions. This article is for reference only)

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