What painkillers should be taken for late stage liver cancer?
Patients with advanced liver cancer are often accompanied by severe pain, and rational use of analgesics is an important means to relieve symptoms and improve quality of life. The following is a compilation of hot topics and structured data on analgesics for advanced liver cancer in the past 10 days across the Internet for the reference of patients and their families.
1. Principles of pain management in late stage of liver cancer
According to the World Health Organization (WHO) three-step analgesic principle, drugs for late-stage liver cancer pain need to be selected according to the degree:
| pain level | Recommended medicine | Representative medicine |
|---|---|---|
| mild pain | non-opioid medications | Acetaminophen, ibuprofen |
| moderate pain | Weak opioids | codeine, tramadol |
| severe pain | strong opioids | Morphine, Fentanyl, Oxycodone |
2. Comparative analysis of commonly used analgesics
The following are the liver cancer painkillers that have been the most discussed in medical forums in the past 10 days:
| Drug name | Applicable stage | Advantages | Things to note |
|---|---|---|---|
| morphine extended release tablets | severe pain | Long-lasting analgesia (8-12 hours) | Be wary of constipation and respiratory depression |
| Fentanyl transdermal patch | severe pain | 72 hours sustained release | Avoid contact with heat sources |
| Tramadol | moderate pain | Less addictive | May cause epileptic seizures |
3. Recently popular adjuvant therapies
Search data in the past 10 days show that the following auxiliary treatment methods have seen a significant increase in attention:
| therapy type | specific plan | Discussion popularity |
|---|---|---|
| nerve block | celiac plexus block | ↑35% |
| Chinese medicine auxiliary | Corydalis, chelidonine | ↑28% |
| psychological intervention | mindfulness stress reduction therapy | ↑42% |
4. Medication precautions
1.personalized medicine: The dose needs to be adjusted according to liver function. Patients with Child-Pugh class C should reduce the dose by more than 50%.
2.Prevent side effects: Opioids should be combined with laxatives, and NSAIDs need to monitor renal function
3.Give medication on time: Administration before pain onset is more effective than rescue medication during pain
5. Dietary suggestions for patients
Recent hot topics in nutrition discussions show that the following foods can help alleviate the side effects of drugs:
| side effects | Recommended food | Mechanism of action |
|---|---|---|
| constipation | Dragon fruit, chia seeds | Dietary fiber promotes peristalsis |
| Nausea and vomiting | ginger, mint | Inhibits 5-HT3 receptors |
6. Latest research trends
1. On August 15, The Lancet published phase II clinical data of the new μ receptor modulator TRV130, which showed that the incidence of nausea was reduced by 40% compared with traditional morphine.
2. The liver-targeted nano-analgesic developed by a domestic team has entered the animal experiment stage and is expected to reduce systemic side effects.
(Note: The specific medication regimen must be strictly followed by the doctor’s instructions. This article is for reference only)
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